さまざまな妊娠期間に乳酸アルミニウムによって口頭で酔っている雌ラットの子孫の発達変化

妊娠中のラットを、妊娠3期間中にアルミニウム乳酸アルミニウム（400 mg AL/kg/日）で経口処理して、子犬の死亡率、体重増加、神経運動成熟、学習能力に対する治療の影響を決定しました。No effect of treatment on litter size, mortality rate, and weight gain of pups was detected.In the negative geotaxis test, the scores of pups from females treated during the second and third weeks of gestation were diminished.運動式の協調とオペラントコンディショニングテストでは、コントロールと3つの治療群の比較の有意差が見つかり、中枢神経系に対する早期中毒の長期的な影響を示しています。

Pregnant rats were treated orally with aluminum lactate (400 mg Al/kg/day) during three periods of gestation to determine the treatment's influence on mortality, weight gain, neuromotor maturation, and learning abilities of their pups. No effect of treatment on litter size, mortality rate, and weight gain of pups was detected. In the negative geotaxis test, the scores of pups from females treated during the second and third weeks of gestation were diminished. In the locomotor coordination and the operant conditioning tests, significant differences in the comparison of controls vs. the three treated groups were found, indicating long-term effects of early intoxication upon the central nervous system.