生体分析用途向けのマイクロ流体紙ベースのデバイス

紙は、マイクロ流体デバイスの建設のための非常に興味深い基質としてますます認識されており、健康診断、環境監視、免疫測定法、食品安全など、さまざまな分野での潜在的な用途があります。このレビューの目的は、紙から構築された分析システムの短い歴史を提示し、製造技術の主な利点と欠点を要約し、比色化学、光電気化学、化学発光、電気化学的出版物などの独占的な検出方法を活用することです。年。最後に、このようなデバイスの生産の将来の傾向について説明します。

Paper has become increasingly recognized as a very interesting substrate for the construction of microfluidic devices, with potential application in a variety of areas, including health diagnosis, environmental monitoring, immunoassays and food safety. The aim of this review is to present a short history of analytical systems constructed from paper, summarize the main advantages and disadvantages of fabrication techniques, exploit alternative methods of detection such as colorimetric, electrochemical, photoelectrochemical, chemiluminescence and electrochemiluminescence, as well as to take a closer look at the novel achievements in the field of bioanalysis published during the last 2 years. Finally, the future trends for production of such devices are discussed.