急性冠動脈症候群における冠動脈病変の重症度とのDAPTと正確なDAPTスコアの矛盾

この研究の目的は、DAPTスコアと正確なDAPTスコアとの矛盾と、急性冠症候群（ACS）の冠動脈病変の重症度との相関を特定することを目的としています。-YEAR Unefentful Dual Antiplatelet Therapy（DAPT）が登録され、Gensiniスコア、狭留容器の数、および左主（LM）疾患に基づいてグループに分割されました。DAPTスコアと正確なDAPTスコアの両方が計算され、各スコアから矛盾する推奨事項を受けている患者の割合をグループ間で比較しました。狭窄船の。同様に、25歳以上の正確なダップスコアを持つ患者の割合と同様に、正確なダップスコアは、ジェンシニスコアと狭窄容器の数に関連していました。DAPTスコア2以上の患者の割合と正確なDAPTスコア≥25は、Gensiniスコアに関連していましたが、狭窄血管の数と有意な関連はありませんでした（それぞれP = .006およびP = .075）。これらの前述の項目のいずれもLM疾患に関連していませんでした。DAPTスコアと正確なダップスコアの矛盾は頻繁であり、冠動脈疾患の重症度に関連しています。適切な臨床決定を個別化する必要があります。

This study aimed to identify the correlation of contradiction between DAPT score and PRECISE-DAPT score with the severity of coronary lesion in acute coronary syndromes (ACS).In total, 458 patients with ACS after a percutaneous coronary intervention (PCI) who had tolerated 1-year uneventful dual antiplatelet therapy (DAPT) were enrolled and divided into groups based on the Gensini score, number of stenosed vessels, and left main (LM) disease. Both DAPT score and PRECISE-DAPT score were calculated and the proportion of patients receiving conflicting recommendations from each score was compared among the groups.DAPT score as well as the proportion of patients with DAPT score ≥2 were associated with the Gensini score and the number of stenosed vessels. Similarly, PRECISE-DAPT score as well as the proportion of patients with PRECISE-DAPT score ≥25 were associated with the Gensini score and the number of stenosed vessels. The proportion of patients with DAPT score ≥2 along with PRECISE-DAPT score ≥25 were associated with Gensini score, but they had no significant association with the number of stenosed vessels (P = .006 and P = .075, respectively). None of those aforementioned items were associated with LM disease.The inconsistencies of DAPT scores and PRECISE-DAPT scores are frequent and associated with the severity of coronary disease, represented by the Gensini score. Appropriate clinical decisions should be individualized.