[アレルギー性起源の好酸球性膀胱炎]

好酸球性膀胱炎は、そのうち35症例が発表されており、その慢性と造血の重要性について顕著な再発性膀胱炎です。尿は通常滅菌され、血液好酸球増加症が頻繁に存在します。組織学では、好酸球による洗浄壁の浸潤は病的です。corticoステロイド治療の不規則な結果を考慮して、原因因子の検索が必要です。寄生虫の侵入は疑われていますが、実際に証明されることはなく、アレルギーの起源はおそらく頻繁に見逃されます。ペニシリンとクロメタシンへのアレルギーがそれぞれ初めて実証され、これらの薬物の撤退後に状態が沈静化した好酸球性膀胱炎の2例を報告します。

Eosinophilic cystitis, of which 35 cases have been published, is a recurrent cystitis remarkable for its chronicity and for the importance of haematuria; the urine is usually sterile and blood eosinophilia frequently present; at histology, infiltration of the vesical wall by eosinophils is pathognomonic. In view of the irregular results of cortico-steroid treatment, a search for causative factors is required. Parasitic infestation has been suspected but never actually proven, and an allergic origin probably is frequently missed. We report two cases of eosinophilic cystitis where allergy to penicillin and clometacin respectively could be demonstrated for the first time and in which the condition subsided after withdrawal of these drugs.